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Company ReportsKiniksa Pharmaceuticals

Kiniksa Pharmaceuticals(KNSA)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Arcalyst	Rilonacept	2008-02-27		Inborn genetic diseases , Inflammation , Cryopyrin-associated periodic syndromes

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

rheumatoid arthritis

,

,

respiratory insufficiency

,

severe acute respiratory syndrome-related coronavirus

,

,

,

respiratory distress syndrome

,

viral pneumonia

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

,

,

myeloid leukemia acute

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

angelman syndrome

,

huntington disease

,

developmental disabilities

,

mental disorders

,

neurodevelopmental disorders

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

non-small-cell lung carcinoma

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

multiple myeloma

,

plasma cell neoplasms

,

follicular lymphoma

,

diabetes mellitus

,

non-hodgkin lymphoma

,

alzheimer disease

,

sickle cell anemia

,

,

type 2 diabetes mellitus

,

paroxysmal hemoglobinuria

,

,

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

brain neoplasms

,

unknown primary neoplasms

,

stomach neoplasms

,

small cell lung carcinoma

,

,

breast neoplasms

,

,

colorectal neoplasms

,

,

triple negative breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

multiple sclerosis

,

myeloid leukemia

,

rheumatoid arthritis

,

,

chronic renal insufficiency

,

kidney diseases

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

renal cell carcinoma

,

,

,

,

,

,

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

cerebrovascular disorders

,

giant cell arteritis

,

polymyalgia rheumatica

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

chronic hepatitis

,

,

,

,

,

chronic hepatitis c

,

neoplasm metastasis

,

renal insufficiency

,

chronic kidney failure

,

chronic hepatitis b

,

iron-deficiency anemia

,

lymphatic diseases

,

iron deficiencies

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

interstitial lung diseases

,

,

,

acquired immunodeficiency syndrome

,

liver cirrhosis

,

spinal muscular atrophies of childhood

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

,

,

myeloid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia acute

,

mantle-cell lymphoma

,

,

myeloid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia acute

hepatic insufficiency

,

renal insufficiency

,

castration-resistant prostatic neoplasms

,

,

,

,

,

unknown primary neoplasms

,

immunomodulation

,

gram-positive bacterial infections

,

t-cell lymphoma peripheral

,

,

merkel cell carcinoma

,

mycosis fungoides

,

clear cell sarcoma

,

myelodysplastic syndromes

,

,

,

pulmonary sarcoidosis

,

lyme neuroborreliosis

,

hypertriglyceridemia

,

,

granuloma annulare

,

mycobacterium avium complex

,

thoracic neoplasms

,

pelvic neoplasms

,

,

,

brain neoplasms

,

stomach neoplasms

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

urinary bladder neoplasms

,

multiple myeloma

,

neoplasm metastasis

,

ovarian neoplasms

,

thyroid neoplasms

,

,

plasma cell neoplasms

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

esophageal neoplasms

,

borrelia infections

,

endometrial neoplasms

,

thyroid diseases

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

uveal neoplasms

,

respiratory syncytial viruses

,

,

,

transitional cell carcinoma

,

kidney diseases

,

small cell carcinoma

,

adenocarcinoma of lung

,

large-cell lymphoma anaplastic

,

,

,

pheochromocytoma

,

,

healthcare-associated pneumonia

,

systemic lupus erythematosus

,

alopecia areata

,

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

oligodendroglioma

,

,

hemangioblastoma

,

urogenital neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

germ cell and embryonal neoplasms

,

carcinoid tumor

,

urethral neoplasms

,

ureteral neoplasms

,

alveolar soft part sarcoma

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cholangiocarcinoma

,

gene rearrangement

,

lobular carcinoma

,

plasma cell leukemia

,

medulloblastoma

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

intraductal carcinoma noninfiltrating

,

b-cell lymphoma

,

cutaneous lupus erythematosus

,

keratoconjunctivitis

,

,

respiratory tract infections

,

,

,

,

hidradenitis suppurativa

,

,

meningococcal infections

,

neoadjuvant therapy

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

multidrug-resistant tuberculosis

,

von hippel-lindau disease

,

,

,

neurodermatitis

,

,

urologic neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

,

benign fibrous histiocytoma

,

,

malignant fibrous histiocytoma

,

myeloid leukemia accelerated phase

,

,

malignant mesothelioma

,

,

urinary bladder diseases

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

second primary neoplasms

,

pulmonary tuberculosis

,

hematologic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

mouth neoplasms

,

,

penile neoplasms

,

plexiform neurofibroma

,

,

testicular neoplasms

,

solitary fibrous tumors

,

,

hemangiopericytoma

,

male urogenital diseases

,

urogenital diseases

,

adenoid cystic carcinoma

,

,

hemangiosarcoma

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

post-acute covid-19 syndrome

,

,

colorectal neoplasms

,

,

atopic dermatitis

,

,

,

,

kidney neoplasms

,

prostatic neoplasms

,

squamous cell carcinoma

,

liver neoplasms

,

pancreatic neoplasms

,

hepatocellular carcinoma

,

,

psoriatic arthritis

,

squamous cell neoplasms

,

squamous cell carcinoma of head and neck

,

,

male breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myeloid leukemia chronic-phase

,

juvenile arthritis

,

,

,

bacterial pneumonia

,

,

mycobacterium avium-intracellulare infection

,

immune system diseases

,

inborn genetic diseases

,

genetic skin diseases

,

eczematous skin diseases

,

hypersensitivity

,

immediate hypersensitivity

,

islet cell carcinoma

,

ankylosing spondylitis

,

bacterial infections

,

pancreatic ductal carcinoma

,

,

,

febrile neutropenia

,

,

mycobacterium infections

,

adenosquamous carcinoma

,

large cell carcinoma

,

nervous system diseases

,

optic nerve diseases

,

disease progression

,

cardiovascular diseases

,

immunologic deficiency syndromes

,

breast neoplasms

,

healthy volunteers/patients

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

,

rheumatoid arthritis

,

,

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

bcr-abl positive chronic myelogenous leukemia

,

,

ulcerative colitis

,

,

,

myeloid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

non-hodgkin lymphoma

,

kidney transplantation

,

philadelphia chromosome

,

islet cell adenoma

,

intraabdominal infections

,

mantle-cell lymphoma

,

,

spondylarthritis

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

,

,

,

ventilator-associated pneumonia

,

chronic hepatitis c

,

,

axial spondyloarthritis

,

,

premature birth

,

bacterial vaginosis

,

vaginal diseases

,

,

infectious skin diseases

,

soft tissue infections

,

,

,

community-acquired infections

,

staphylococcal infections

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

bacterial skin diseases

,

,

asymptomatic infections

,

,

,

respiratory tract diseases

,

neurodermatitis

,

,

,

chronic urticaria

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

pancreatic neoplasms

,

head and neck neoplasms

,

,

chronic hepatitis b

,

chronic hepatitis

,

small cell lung carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

stomach neoplasms

,

,

liver neoplasms

,

,

,

,

esophageal squamous cell carcinoma

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

uterine cervical neoplasms

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

autoimmune hepatitis

,

hepatocellular carcinoma

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

rheumatoid arthritis

,

,

,

,

paroxysmal hemoglobinuria

,

,

,

,

,

alzheimer disease

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

colonic neoplasms

,

deficiency diseases

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

hemolytic-uremic syndrome

,

,

,

atypical hemolytic uremic syndrome

,

,

,

breast neoplasms

,

,

,

juvenile arthritis

,

triple negative breast neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

mantle-cell lymphoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

metabolic syndrome

,

,

large b-cell lymphoma diffuse

,

,

neoplasm metastasis

,

,

,

,

,

non-small-cell lung carcinoma

,

brain neoplasms

,

b-cell lymphoma

,

neuroendocrine tumors

,

myelodysplastic syndromes

,

,

gastrointestinal stromal tumors

,

breast neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

kidney transplantation

,

,

,

choroidal neovascularization

,

pathologic neovascularization

,

liver cirrhosis

,

,

,

chronic hepatitis b

,

,

,

beta-thalassemia

,

,

,

psoriatic arthritis

,

multiple sclerosis

,

,

cardiovascular diseases

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

spondylarthritis

,

,

axial spondyloarthritis

,

migraine disorders

,

macular degeneration

,

atherosclerosis

,

,

myocardial infarction

,

diabetes mellitus

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

,

myeloid leukemia chronic-phase

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